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Acceptable scientific tests have not been executed on the relationship of age to the consequences of codeine while in the pediatric inhabitants. It should not be Utilized in kids young than twelve many years of age. Safety and efficacy haven't been set up.

Zbog sličnosti oksidativnih procesa, diazepam kompetitivno inhibira metabolizam ketamina. Premedikacija sa diazepamom dovodi do produženog poluvremena eliminacije ketamina, što za rezultat ima njegovo pojačano dejstvo. Pojačana sedacija.

Nakon ponavljane primene leka tokom nekoliko nedelja može doći do određenog gubitka hipnotičkih efekata.

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The presence of other health-related issues might affect using this medication. Ensure you tell your doctor Should you have some other clinical difficulties, Specifically:

Ova interakcija je od malog značaja kod zdravih osoba, ali nije jasno da li drugi faktori, kao što su starije životno doba ili ciroza jetre, povećavaju rizik od pojave neželjenih dejstava prilikom istovremene upotrebe.

Fenitoin je poznati induktor CYP3A4 i ubrzava metabolizam diazepama u jetri. Smanjeno dejstvo diazepama. Diazepam deluje na metabolizam fenitoina na nepredvidiv način: metabolizam fenitoina pod dejstvom diazepama može biti ubrzan ili usporen, ili ostati nepromenjen.

Acquire this drugs only as directed by your medical professional. Don't take much more of it, don't just take it far more usually, and do not acquire it for an extended time than your doctor purchased.

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Some Unintended effects could manifest that usually tend not to need to have health-related notice. These Unintended effects may perhaps disappear for the duration of remedy as The body adjusts into the medicine. Also, your wellbeing treatment professional could possibly tell you about methods to avoid or reduce some of these Negative effects.

Diazepam se ne sme koristiti kao monoterapija u terapiji depresije i anksioznosti udružene sa depresijom, jer kod ove grupe pacijenata može uzrokovati pojavu suicida.

However it helps A lot of people, this medication could at times cause dependancy. This risk may very well be better In case you have a material use dysfunction (for example overuse of or addiction to drugs/Alcoholic beverages).

Working with an excessive amount of of this medication may possibly induce reduced infertility (unable to have little ones). Speak with your doctor prior to making use of this medication if you intend to possess young children.

Individuals struggling from rest apnoea syndrome, a disorder where respiratory pauses for temporary read more intervals throughout slumber.

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